Description
1-Dodecylimidazole is grouped with the imidazole organic compounds, containing an imidazole 1,3-C3N2 ring produced by natural products like alkaloids. Imidazole is amphoteric and aromatic. When an additional carbon and two hydrogens bind to the ring of this compound, 1-Dodecylimidazole can produce a 1-dodecyl-3-methylimidazolium cation.
As an antifungal, 1-Dodecylimidazole can inhibit sterol C14 demethylation at low levels, 2,3-oxidosqualene cyclization and subsequent transmethylation when the quantity is raised. This has been postulated as a result of its binding to sterol carrier proteins. It functions as a hypocholesterolaemic agent by inhibiting cholesterol biosynthesis at the level of 2,3-oxidosqualene sterol cyclase.
This substance has been an effective antimalarial agent within 15 minutes of administration to in vitro cultures of the pathogen. It exhibited inhibition of protein synthesis and the alkalinization of the parasitic food vacuole. The chemical has also been observed functioning as a lysosomotropic detergent against Saccharomyces cerevisiae.
Product Specifications1-DodecylimidazoleN-Dodecylimidazole1-dodecyl-1H-imidazole
Formula: C15H28N2
MW: 236.40 g/mol
Storage/Handling: Store at 4°C.
PubChem Chemical ID:78002
