Chlorimuron ethyl is a sulfonylurea organic compound used as an insulin enhancing compound and also for herbicide. Promotion of insulin release by chlorimuron ethyl occurs by inhibiting ATP-sensitive potassium channels, which depolarizes the cell membrane of β-islet pancreatic cells. Depolarization is followed by a large influx of calcium that signals the cell to exocytose insulin vesicles.
Chlorimuron ethyl has also been used to induce plant death by inhibiting acetolactate synthase (ALS). The enzyme ALS synthesized branched chain amino acids, such as valine and leucine, which are integral to forming key enzymes in photosynthesis and aerobic respiration. Scarcity of these vital amino acids leads to reactive oxygen species generation and diminished DNA synthesis.
Product SpecificationsChlorimuronethyl (Sulfonylurea)Chlorimuron ethyl ester
Formula: C15H15ClN4O6S
MW: 414.82 g/mol
Storage/Handling: Store at 4°C.Soluble in methanol.
PubChem Chemical ID: 56160
IPTG, X-Gal and X-Gluc
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没错！最开始，Gold Biotechnology只生产这三个产品，30年后的今天，Goldbio的产品已经超过3000种，涵盖：
琼脂糖树脂
抗生素
生化试剂
缓冲液
克隆与诱导
培养基添加剂
洗涤剂
DNA蛋白质电泳
酶、抑制剂和底物
生长因子
植物研究
蛋白质表达与纯化
还原剂……
目前Goldbio最核心的产品是：荧光素钾盐，X-gluc， 双丙氨磷，草胺磷 和 X-α-gal
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