Camptothecin sodium is sodium salt of an alkaloid compound camptothecin, which is used for cancer research. Camptothecin is produced from endosymbiotic Ascomycota (Phycomycete) fungi present in the tree Camptotheca acuminata or the plant Mappia foetida.
Camptothecin sodium is a topoisomerase I inhibitor in DNA synthesis. It has been shown to bind and stabilize a topoisomerase I-DNA complex in vitro, preventing the enzyme from reannealing DNA strands. This inhibition specifically effects the S-phase of cell development and ultimately results in apoptosis due to damaged DNA.
Product SpecificationsCamptothecinsodiumCamptothecin sodium saltSodiumcamptothecin
Formula: C20H17N2NaO5
MW: 388.35 g/mol
Storage/Handling: Store desiccated at room temperature.
PubChem Chemical ID: 23705698
IPTG, X-Gal and X-Gluc
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没错！最开始，Gold Biotechnology只生产这三个产品，30年后的今天，Goldbio的产品已经超过3000种，涵盖：
琼脂糖树脂
抗生素
生化试剂
缓冲液
克隆与诱导
培养基添加剂
洗涤剂
DNA蛋白质电泳
酶、抑制剂和底物
生长因子
植物研究
蛋白质表达与纯化
还原剂……
目前Goldbio最核心的产品是：荧光素钾盐，X-gluc， 双丙氨磷，草胺磷 和 X-α-gal
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