Spectinomycin is an aminocyclitol antibiotic isolated from Streptomyces spectabilis. It is effective against gram-positive and gram-negative bacteria, but most commonly used against Gonococcus species.It has also been used to monitor cell fate during leaf development and as a selection marker in plants to display successful transformation of the Spcr gene.
Spectinomycin functions by binding the 30s ribosomal subunit, inhibiting tRNA translation and protein synthesis.Resistance to this antibiotic is conferred through the aadA gene and mutated rpsE gene.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
TESTED AGAINST BOTH SENSITIVE AND RESISTANT CELLS.
Product Specifications:Spectinomycin Dihydrochloride Pentahydrate
Formula: C14H24N2O7 · 2HCl · 5H2OMW: 495.35 g/molStorage/Handling: Store desiccated at -20°C.Soluble in water. PubChem Chemical ID:30971
IPTG, X-Gal and X-Gluc
©蚂蚁淘
没错!最开始,Gold Biotechnology只生产这三个产品,30年后的今天,Goldbio的产品已经超过3000种,涵盖:
琼脂糖树脂
抗生素
生化试剂
缓冲液
克隆与诱导
培养基添加剂
洗涤剂
DNA蛋白质电泳
酶、抑制剂和底物
生长因子
植物研究
蛋白质表达与纯化
还原剂……
目前Goldbio最核心的产品是:荧光素钾盐,X-gluc, 双丙氨磷,草胺磷 和 X-α-gal