Ethambutol is an antitubercular antibiotic effective against Mycobacterium species, especially Mycobacterium tuberculosis.It has been used to study multidrug-resistant tuberculosis and in combination with other drugs to decrease the risk of developing additional multidrug resistant species.
The mechanism of action of ethambutol starts with inactivation of arabinosyl transferase, an enzyme required to transport mycolic acids to the cell wall.Upon inactivation of this enzyme, cell wall permeability increases allowing toxic substances to enter the cell.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
Product SpecificationsEthambutol
MOLECULAR BIOLOGY GRADE
Formula: C10H24N2O2
MW: 204.31 g/mol
Storage/Handling: Store at 2-8°C.
PubChem Chemical ID: 14052
IPTG, X-Gal and X-Gluc
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没错!最开始,Gold Biotechnology只生产这三个产品,30年后的今天,Goldbio的产品已经超过3000种,涵盖:
琼脂糖树脂
抗生素
生化试剂
缓冲液
克隆与诱导
培养基添加剂
洗涤剂
DNA蛋白质电泳
酶、抑制剂和底物
生长因子
植物研究
蛋白质表达与纯化
还原剂……
目前Goldbio最核心的产品是:荧光素钾盐,X-gluc, 双丙氨磷,草胺磷 和 X-α-gal