Imipenem is a carbapenem β-lactam antibiotic with a broad target spectrum.It has been shown to be effective against ESBL-producing Enterobacteriaceae and gram-negative and gram-positive organisms.Imipenem has also been shown to be effective against bacteria from the genus Burkholderia.Resistance to imipenem is conferred through the loss of the OprD porin protein.

β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product SpecificationsImipenemImipenem Monohydrate

MOLECULAR BIOLOGY GRADE

Formula: C₁₂H₁₇N₃O₄S ∙ H₂O

MW: 317.36 g/mol

Storage/Handling: Store at -20°C.

PubChem Chemical ID: 5282372

IPTG, X-Gal and X-Gluc

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没错！最开始，Gold Biotechnology只生产这三个产品，30年后的今天，Goldbio的产品已经超过3000种，涵盖：

琼脂糖树脂

抗生素

生化试剂

缓冲液

克隆与诱导

培养基添加剂

洗涤剂

DNA蛋白质电泳

酶、抑制剂和底物

生长因子

植物研究

蛋白质表达与纯化

还原剂……

目前Goldbio最核心的产品是：荧光素钾盐，X-gluc， 双丙氨磷，草胺磷 和 X-α-gal