Ampicillin sodium is a member of the extended-spectrum β-lactam family and similar in structure to penicillin.It is used in the selection of antibiotic cell hybrids and has a high rate of action against many gram-negative bacterial strains. Ampicillin sodium targets non-ESBL (Extended Spectrum β-lactamase) bacteria including Staphylococcus and Streptococcus species and medically important enteric pathogens such as Shigella and Salmonella.It has been found to be effective against certain β-lactam sensitive VRE or vancomycin resistant Enterococcus species. Resistance to ampicillin is routinely utilized as a selectable marker to confirm successful cell transformation. Ampicillin Sodium is freely soluble in water.

β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Resistance to β-lactam antibiotics occurs in the presence of cells containing plasmid encoded extended spectrum β-lactamases or ESBLs.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product SpecificationsSodium Ampicillin

Formula: NaC₁₆H₁₈N₃O₄S

MW: 371.39 g/mol

Storage/Handling: Store desiccated at -20°C. Soluble in water.

PubChem Chemical ID: 23663979

Ampicillin Stock Solution - 100 mg/ml

Instructions

1. Weigh 1 g of Ampicillin (Ampicillin (Sodium), GoldBio Catalog # A-301 [CAS 69-52-3, mw.= 371.4]).
2. Add 10 ml of sterile H₂O. Dissolve completely.
3. Prewet a 0.22 μm syringe filter by drawing through 5-10 ml of sterile H₂O and discard water.
4. Sterilize Ampicillin Stock through the prepared 0.22 μm syringe filter.
5. Stock may be kept at -80°C for 1 year.
   • Note: Ampicillin solutions degrade 13% after one week at -20°C.

IPTG, X-Gal and X-Gluc

©蚂蚁淘

没错！最开始，Gold Biotechnology只生产这三个产品，30年后的今天，Goldbio的产品已经超过3000种，涵盖：

琼脂糖树脂

抗生素

生化试剂

缓冲液

克隆与诱导

培养基添加剂

洗涤剂

DNA蛋白质电泳

酶、抑制剂和底物

生长因子

植物研究

蛋白质表达与纯化

还原剂……

目前Goldbio最核心的产品是：荧光素钾盐，X-gluc， 双丙氨磷，草胺磷 和 X-α-gal