Ribostamycin is an aminoglycoside antibiotic isolated from Streptomyces ribosifidicus.It is a broad-spectrum antibiotic targeting gram-positive and gram-negative bacteria.Ribostamycin has been used to in pharmacokinetic studies and to study kidney toxicity.It is also an inhibitor of protein disulfide isomerase (PDI).

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product SpecificationsRibostamycin Sulfate

MOLECULAR BIOLOGY GRADE

Formula: C₁₇H₃₄N₄O₁₀ ∙ H₂SO₄

MW: 552.55 g/mol

Storage/Handling: Store at 2-8°C.

PubChem Chemical ID: 18469537

IPTG, X-Gal and X-Gluc

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没错！最开始，Gold Biotechnology只生产这三个产品，30年后的今天，Goldbio的产品已经超过3000种，涵盖：

琼脂糖树脂

抗生素

生化试剂

缓冲液

克隆与诱导

培养基添加剂

洗涤剂

DNA蛋白质电泳

酶、抑制剂和底物

生长因子

植物研究

蛋白质表达与纯化

还原剂……

目前Goldbio最核心的产品是：荧光素钾盐，X-gluc， 双丙氨磷，草胺磷 和 X-α-gal