Amphotericin B is a polyene antifungal isolated from Streptomyces species.While it has been suggested that Amphotericin B interacts with ergosterol of the fungal cell membrane leading to an altered cell membrane permeability and death, more recent studies show that the mechanism behind amphotericin B’s fungicidal activity is more complex.It is most effective against fungi and yeast and is often used against opportunistic fungal infections and leishmaniasis.Additionally, amphotericin B can be used to prevent growth of F. oxysporum in chickpea and P. triticina in wheat.

Amphotericin B is often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product SpecificationsAmphotericin B, USP Grade

Formula: C₄₇H₇₃NO₁₇

MW: 924.08 g/mol

This product is soluble in DMSO or DMF

PubChem CID: 5280965

IPTG, X-Gal and X-Gluc

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没错！最开始，Gold Biotechnology只生产这三个产品，30年后的今天，Goldbio的产品已经超过3000种，涵盖：

琼脂糖树脂

抗生素

生化试剂

缓冲液

克隆与诱导

培养基添加剂

洗涤剂

DNA蛋白质电泳

酶、抑制剂和底物

生长因子

植物研究

蛋白质表达与纯化

还原剂……

目前Goldbio最核心的产品是：荧光素钾盐，X-gluc， 双丙氨磷，草胺磷 和 X-α-gal