The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt"s lymphomas, suggesting its importance in the normal function of this gene.
Product Namec-Myc Polyclonal Antibodyc-Myc Rabbit pAbMRTL; MYCC; bHLHe39;c-Myc; MYC
Host Species Rabbit
Purification Method Affinity purification
IsotypeIgG
Storage/HandlingStore at -20℃.Avoid freeze / thaw cycles.
Storage BufferPBS with 0.02% sodium azide, 50%glycerol, pH7.3.
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 1-100 of human c-Myc (NP_002458.2).
Sequence MDFFRVVENQ QPPATMPLNV SFTNRNYDLD YDSVQPYFYC DEEENFYQQQ QQSELQPPAP SEDIWKKFEL LPTPPLSPSR RSGLCSPSYV AVTPFSLRGD
Gene ID: 4609
Swiss Protein: P01106
Calculated MW: 48 kDa/50 kDa
Observed MW: 49 kDa
IPTG, X-Gal and X-Gluc
©蚂蚁淘
没错!最开始,Gold Biotechnology只生产这三个产品,30年后的今天,Goldbio的产品已经超过3000种,涵盖:
琼脂糖树脂
抗生素
生化试剂
缓冲液
克隆与诱导
培养基添加剂
洗涤剂
DNA蛋白质电泳
酶、抑制剂和底物
生长因子
植物研究
蛋白质表达与纯化
还原剂……
目前Goldbio最核心的产品是:荧光素钾盐,X-gluc, 双丙氨磷,草胺磷 和 X-α-gal