GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
RecombinantMurine Sonic HedgeHog (SHH)rMuSHHHhg1Hxl3
Members of the Hedgehog (Hh) family are highly conserved proteins that are widely represented throughout the animal kingdom. The three known mammalian Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh), are structurally related and share a high degree of amino acid sequence identity. Each Hh protein has a unique expression pattern and distinct biological role within its respective region of secretion. All Hh proteins use the same signaling pathway and can substitute for each other in experimental systems. Shh has been found to have a critical role in development, acting as a morphogen in the patterning of limbs, brain structure, facial structure, lungs, spinal cord, thalamus and the teeth. Shh has been shown to attract commissural axons in the developing spinal cord by attracting or repelling retinal ganglion cell (RGC) axons depending on concentration. Murine SHH is frequently coexpressed with BMP2, BMP4, and BMP6.
Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~19.8 kDa (176amino acids)
Purity: >95% by SDS-PAGEand HPLC analyses
Biological Activity: Fully biologicallyactive when compared to standard. The ED50 as determined byinducing alkaline phosphatase production of murine C3H10T1/2 cells is 0.5-1.0 μg/ml.
Storage/Handling: Store desiccated at-20°C.
MGD: 98297
NOT FOR HUMAN USE!
Additional resources for this protein may be found at:OMIM
IPTG, X-Gal and X-Gluc
©蚂蚁淘
没错!最开始,Gold Biotechnology只生产这三个产品,30年后的今天,Goldbio的产品已经超过3000种,涵盖:
琼脂糖树脂
抗生素
生化试剂
缓冲液
克隆与诱导
培养基添加剂
洗涤剂
DNA蛋白质电泳
酶、抑制剂和底物
生长因子
植物研究
蛋白质表达与纯化
还原剂……
目前Goldbio最核心的产品是:荧光素钾盐,X-gluc, 双丙氨磷,草胺磷 和 X-α-gal