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GoldBio/CSF1 (M-CSF), Murine/250 μg/1320-09-250

GoldBio/CSF1 (M-CSF), Murine/250 μg/1320-09-250
  • GoldBio/CSF1 (M-CSF), Murine/250 μg/1320-09-250
商品介绍

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Murine Colony Stimulating Factor 1 (Macrophage)Macrophage Colony Stimulating Factor, M-CSF

RecombinantMurine Colony Stimulating Factor 1 (Macrophage) (CSF1), formerly called Macrophage Colony Stimulating Factor (M-CSF), is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. It is produced by osteoblasts (as a result of endocrine stimulation by parathyroid hormone) exerts paracrine effects on osteoclasts and can interact with CSF1R. CSF1 is a four α-helical bundle cytokine and its active form is found extracellularly as a disulfide-linked homodimer. Four transcript variants encoding three different isoforms have been reported for CSF1 gene. Although forms may vary, all of them contain the N-terminal 150 amino acid portion that is necessary and sufficient for interaction with the receptor. The first 229 amino acids of mature mouse CSF1 shares 87%, 83%, 82% and 81% sequence identity with corresponding regions of rat, dog, cow and human CSF1, respectively. Human CSF1 is active in the mouse, but mouse CSF1 is reported to be species-specific.

Formulation: Sterile filtered whitelyophilized powder. Purified and tested for use in cell culture.

Sequence: KEVSEHCSHMIGNGHLKVLQ QLIDSQMETS CQIAFEFVDQ EQLDDPVCYL KKAFFLVQDI IDETMRFKDN TPNANATERLQELSNNLNSC FTKDYEEQNK ACVRTFHETP LQLLEKIKNF FNETKNLLEK DWNIFTKNCN NSFAKCSSRDVVTKPDCNCL YPKATPSSDP ASASPHQPPA PSMAPLAGLA WDDSQRTEGS SLLPSELPLR IEDPGSAKQRPPRSTCQTLE

MW: ~52.0 kDa (a disulfide-linked homodimer consisting of two 230amino acid polypeptide chains).

Purity: >95% by SDS-PAGEand HPLC analyses.

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine M-NFS-60 cells is less than2.0 ng/ml, corresponding to a specific activity of >5.0 × 109 IU/mg.

Accession Number: Q3U4F9

MGI ID: 1339753

Source: Escherichia coli

Storage/Handling: This lyophilized preparationis stable at 2-8°C, but should be kept at -20°C for long term storage. Thereconstituted sample can be apportioned into working aliquots and stored at-80°C for up to 6 months. Avoid repeated freeze/thaw cycles.

Reconstitution: The sample shouldbe briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitutein a siliconized tube using PBS that contains a 0.1% BSA to a concentration of0.1-1.0 mg/mL. Reconstituted solutions are stable for up to one week at 2-8°C.Stock solutions should be aliquoted and stored at -80°C. Further dilutionsshould be made in appropriate buffered solutions containing BSA or serum.

Additional resources for this product may be found at:

OMIM

NOT FOR HUMAN USE!

品牌介绍

About GoldBio:

GoldBio Research

Gold Biotechnology shares a vision with every researcher: Each facet of life science research will introduce us to a future of impactful discovery and learning, benefiting the entire world. And our vision will materialize sooner if a researcher’s passion is not sullied by worry over the quality of their reagents, especially the cost for quality. This is why we’re here! We believe in a future of change and prosperity, and we want to help you get there by being a resource for high-quality products at exceptional prices. By providing our customers with only the best chemicals possible, tested in GoldBio labs to assure our own quality specifications are met, you can be sure your research will go off without a hitch.

Mission Statement:

"At GoldBio, we strive to exceed the expectations of our customers, vendors and strategic partners through quality of products, excellent service and attention to detail. Our sustainable business model and relationships with others in the supply chain allow us to provide researchers and scientists with uniquely low prices, while maintaining the highest quality in the industry. We stand behind all our products to the fullest extent with the hope that they will be used in discoveries that benefit all."

Our Philosophy:

Provide the highest quality product
Maintain low costs to pass along to the researcher
Be an advocate for the industry
Support our customers as any loyal business partner
Be an ally to businesses in the industry
Put forth products with hope
Look towards the future
We look toward the future with hope as we send out our products with the intent that they will be used in great discovery. We are a small company dedicated to the success of those whom we supply. So we provide high-quality low cost materials to scientists and researchers. We give our customers the best so they can discover, invent, and innovate. Because that is what it is about for us...The Discovery.

Commitment to Quality:

We are dedicated to providing our customers with the highest-quality products available. We test our products from our network of trusted global suppliers to assure they meet our quality specifications. We stand behind all of our products knowing that our reputation lies on the success of your experiments.

History:

Dr. Paul Gold

During the 1980s, Dr. Paul Gold stepped out from behind the bench believing researchers needed a low-cost, high-quality alternative for chemicals and reagents. Recognizing his knack for business, he began brewing the idea for a company during a time when startup incubators were nearly unheard of, and the Internet, social media and crowdfunding didn’t exist. Armed with a supportive wife, generous family members and helpful people within his network, Dr. Gold established GoldBio in 1986.

The original main office was situated in the former St. Louis Technology Center (now the location for the St. Louis Science Center), while the first lab space was located at St. Louis University. The ambitious startup began its journey selling three products: IPTG, X-Gal and X-Gluc.

Now, after almost 30 years, GoldBio has evolved significantly, expanding its catalog from three products to more than 3000 products. Throughout its history, GoldBio’s success has relied on its commitment to the success of those whom we supply. At GoldBio, we believe that putting our quality products in capable hands leads to discoveries that impact the entire world。

 


苏州蚂蚁淘生物科技有限公司是一家创新型高科技生物公司,以常规生物学实验外包与生物学试剂为基础,放眼于生命科学领域的前沿技术服务,公司技术骨干有着多年的生物学科研背景,毕业于国内外名牌大学,并且有着丰富的项目经验,了解国内外科研行情,我公司力求为每一个客户提专业、针对性的实验方案。我公司以技术服务为支点,和国内外多家生物试剂公司有着密切的业务往来.公司特色技术服务包括:抗体药物研发、噬菌体抗体库、蛋白表达与传化、抗体制备、高通量测序、组学研究、生物信息学分析与方法建立、基础分子生物学技术外包、化学中间体合成、原料药物研发、论文编写等。我公司秉承”诚信做人,认真做事,服务至上“,希望用我们的专业知识和项目经验为国内科研客户解决科研问题,祝您科研之路畅通无阻!


GoldBiotechnology【GoldBio】公司中国总代理

欢迎广大客户咨询订货,在线QQ:3507623898

4000-520-616

GoldBiotechnology公司成立于1986年,最初总办公室位于前圣路易斯技术中心,第一个实验室位于于圣路易斯大学。这家公司最初只销售三款产品:IPTGX-GalX-Gluc。经过30多年的发展,现有产品多达3000种,我们致力于为客户提供zui优质的产品,为客户提供zui优质的服务,我们相信优质的产品放在有能力的人手中会带来影响世界的发现。

GoldBiotechnology三大黄金产品:IPTG,X-GalandX-Gluc

最开始,GoldBiotechnology只生产这三个产品,30年后的今天,GoldBio的产品已经超过3000种,涵盖:

琼脂糖树脂 抗生素 生化试剂 缓冲液 克隆与诱导 培养基添加剂 洗涤剂 DNA蛋白质电泳 酶、抑制剂和底物 生长因子 植物研究 蛋白质表达与纯化 还原剂……

目前GoldBio最核心的产品是:荧光素钾盐,X-gluc,双丙氨磷,草胺磷和X-α-gal


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