Clotrimazole is an antifungal that targets the cell membrane of a variety of fungi including Candida and Aspergillus.It inhibits the synthesis of ergosterol causing an increase in cell membrane permeability.Additionally, clotrimazole is an activator of MB67 and inhibitor of CYP3A4 and CYP51A1.
Clotrimazole is often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
Product SpecificationsClotrimazole
MOLECULAR BIOLOGY GRADE
Formula: C22H17ClN2
MW: 344.84 g/mol
Storage/Handling: Store at 2-8°C.Protect from light.Clotrimazole is soluble in acetone, alcohol, chloroform, DMF, and ethyl acetate.
PubChem Chemical ID: 2812
IPTG, X-Gal and X-Gluc
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没错！最开始，Gold Biotechnology只生产这三个产品，30年后的今天，Goldbio的产品已经超过3000种，涵盖：
琼脂糖树脂
抗生素
生化试剂
缓冲液
克隆与诱导
培养基添加剂
洗涤剂
DNA蛋白质电泳
酶、抑制剂和底物
生长因子
植物研究
蛋白质表达与纯化
还原剂……
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