Brefeldin A is an antibiotic derived from Penicillium brefeldianum.It is an anti-cancer agent which disrupts protein transport and causes apoptosis of tumor cells.Brefeldin A disrupts the function of the Golgi apparatus and blocks Golgi-COPI activity.ER vesicles are prevented from fusion with the Golgi and are secretion is inhibited.Additionally, Brefeldin A is an ARF inhibitor, sphingomyelin cycle activator, and caspase-3 activator.It has been shown to induce apoptosis in leukemia cells and colon cancer cells.
Product SpecificationsBrefeldin A
MOLECULAR BIOLOGY GRADE
Formula: C16H24O4
MW: 280.36 g/mol
Storage/Handling: Store at 4°C.
Brefeldin A is soluble in DMSO, acetone, or ethanol. It is insoluble in water.
PubChem CID: 5287620
IPTG, X-Gal and X-Gluc
©蚂蚁淘
没错!最开始,Gold Biotechnology只生产这三个产品,30年后的今天,Goldbio的产品已经超过3000种,涵盖:
琼脂糖树脂
抗生素
生化试剂
缓冲液
克隆与诱导
培养基添加剂
洗涤剂
DNA蛋白质电泳
酶、抑制剂和底物
生长因子
植物研究
蛋白质表达与纯化
还原剂……
目前Goldbio最核心的产品是:荧光素钾盐,X-gluc, 双丙氨磷,草胺磷 和 X-α-gal